Conference Schedule and Scientific Program

SATURDAY, JUNE 18, 2005

GRAND BALLROOM	SPECIAL SESSION Co-sponsored by the Protein Society and the American Peptide Society Organized and Chaired by Jeff W. Kelly
08:00 - 08:30  LS1	PROTEIN DESIGN INFORMATION FROM EVOLUTION William Russ
08:30 - 09:00  LS2	STRUCTURE OF AMYLOID FIBRILS TOWARDS DESIGN Roland Riek
09:00 - 09:30  LS3	PROTEIN DESIGN Homme W. Hellinga
09:30 - 10:00  LS4	COMPUTATIONAL TOOLS TO PROTEIN DESIGN Steve Mayo
10:00 - 10:30	REFRESHMENT BREAK IN LECTURE HALL
10:30 - 11:00  LS5	BETA-HAIRPIN DESIGN Andrea Cochran
11:00 - 11:30  LS6	DESIGN OF BETA-SHEETS THAT FOLD AT THE SPEED LIMIT Marcus Jager
11:30 - 12:00  LS7	STRUCTURE BASED DESIGN OF PEPTIDE BOND ISOMERASES Felicia Etzkorn
12:00 - 12:30  LS8	DESIGNING SEQUENCES THAT DO NOT AGGREGATE INTO AMYLOID Fabrizio Chiti
YIMS GRAND BALLROOM	THE DR. BERT L. SCHRAM YOUNG INVESTIGATORS' MINI-SYMPOSIUM Sponsored by the ESCOM SCIENCE FOUNDATION Chairs: John P. Mayer and Alain Fournier
13:00 - 13:15  LY1	CAGED PHOSPOSERINE PEPTIDES AND PROTEINS Deborah Rothman - Barbara Imperiali Massachusetts Institute of Technology
13:15 - 13:30  LY2	INTERACTION BETWEEN A MINIMUM HEVEIN DOMAIN AND CHITOOLIGOSACCHARIDES STUDIED BY NMR AND A NOVEL SURFACE PLASMON RESONANCE METHOD Miquel Vila-Perello - Nuria Aboitiz - Ricardo Gutiérrez-Gallego - Francisco Javier Canada - Jesus Jimenez-Barbero - David Andreu Department of Experimental and Health Sciences; Universitat Pompeu Fabra; Centro Investigaciones Biológicas-CSIC; Pharmacology Unit; IMIM
13:30 - 13:45  LY3	CROSS-REACTIVITY STUDIES OF rMOGED WITH SYNTHETIC PUTATIVE AUTOANTIGENS CSF114(Glc) AND [N31(Glc)]hMOG(30-50) IN MULTIPLE SCLEROSIS PATIENTS’ SERA Barbara Mulinacci - Constanz Breithaupt - Prajna Paramita Pal - Nediljko Budisa - Marta Pazzagli - Benedetta Mazzanti - Paolo Rovero - Luis Moroder - Anna Maria Papini Laboratory of Peptide & Protein Chemistry & Biology; Polo Scientifico; University of Florence; Max-Planck-Institut für Biochemie; D-82152 Martinsried; Germany.; Laboratory of Peptide & Protein Chemistry & Biology.; Laboratory of Peptide & Protein Chemistry & Biology; Università di Firenze.
13:45 - 14:00  LY4	SITE SPECIFIC INTRODUCTION OF UNNATURAL AMINO ACIDS AT SITES CRITICAL TO INSULIN RECEPTOR RECOGNITION AND BIOLOGICAL ACTIVITY Beili Quan - Dave Smiley - Vasily Gelfanov - Richard DiMarchi Indiana University
14:00 - 14:15  LY5	HELICAL PEPTIDE ANALOGS OF GP41 TO DEVELOP AN HIV VACCINE Florence Brunel - Michael Zwick - Dennis Burton - Phil Dawson The Scripps Research Institute; Department of Immunology; The Scripps Research Institute; La Jolla; CA; 92037; U.S.A.; Department of Chemistry; The Scripps Research Institute; La Jolla; CA; 92037; U.S.A.
14:15 - 14:30  LY6	NMR STRUCTURE OF C-TERMINAL PEPTIDE FRAGMENTS FROM E COLI OSMOREGULATORY PROTEIN PROP David Zoetewey - Janet Wood - Robert Hodges University of Colorado Health Sciences Center; University of Guelph Canada
14:30 - 14:45  LY7	PEPTIDE-DERIVED (SULFONYL) AZIDES AS VERSATILE SYNTHONS IN CHEMOSELECTIVE BIOCONJUGATIONS Remco Merkx - Dirk TS Rijkers - Arwin J Brouwer - J. Kemmink - RMJ Liskamp Department of Medicinal Chemistry; Utrecht Institute for Pharmaceutical Sciences; Utrecht University; P.O. Box 80082; 3508 TB Utrecht; The Netherlands
14:45 - 15:00  LY8	Design and Synthesis of Piperazine-Based Small Molecule Peptide Mimetics Targeting the Melanocortin Receptors James Cain - Alexander V. Mayorov - Yeon-Sun Lee - Minying Cai - Jinfa Ying - Victory Hruby University of Arizona
15:00 - 15:30	REFRESHMENT BREAK IN LECTURE HALL
15:30 - 15:45  LY9	BASIS FOR SELECTIVITY OF CATIONIC ANTIMICROBIAL PEPTIDES FOR BACTERIAL VS. MAMMALIAN MEMBRANES Evgenia Glukhov - Charles M. Deber Structural Biology & Biochemistry; Research Institute; Hospital for Sick Children; Toronto; Ontario; Canada
15:45 - 16:00  LY10	TOTAL SOLID PHASE SYNTHESIS OF THE MARINE CYCLODEPSIPEPTIDE IB-01212 Luis J. Cruz, Marta Martinez, Julia Perez, Marta Trujillo, Ricard Rodriguez, Ernest Giralt, Carmen Cuevas, Librada M Cañedo, Fernando Albericio Barcelona Science Park; University of Barcelona; 08028-Barcelona; Spain; Instituto Biomar S. A.; 24231 Onzonilla; León. Spain; Phama Mar; 28770-Colmenar Viejo; Madrid; Spain
16:00 - 16:15  LY11	STUDY OF FUNCTION(S) AND POSSIBLE DESTABILIZING MECHANISMS OF WILDTYPE OP18/STATHMIN AND MUTANT Q18--E IN MICROTUBULE DYNAMICS. Hope Wilson - Douglas A. Thrower - Leslie Wilson California Alliance for Minority Participation (CAMP)
16:15 - 16:30  LY12	A NEW CLASS OF BETA STRAND MIMETICS John Blankenship - William D. Lubell University of Montreal
16:30 - 16:45  LY13	SELF-ASSEMBLED HYDROGELS FROM B-HAIRPIN PEPTIDES: TUNING RESPONSIVENESS AND BULK MATERIAL PROPERTIES BY PEPTIDE DESIGN Karthikan Rajagopal - Bulent Ozbas - Darrin Pochan - Joel Schneider University of Delaware
16:45 - 17:00  LY14	CELLULAR UPTAKE OF CELL-PENETRATING PEPTIDES (CPP) IS DIFFERENTIATION RESTRICTED Christina Foerg Institute of Pharmaceutical Sciences; Swiss Federal Institute of Technology Zurich (ETH Zurich)
17:00 - 17:15  LY15	IN VITRO TRANSLATION OF ALL-UNNATURAL PEPTIDES Matthew Hartman - Kristopher Josephson - Jack Szostak Howard Hughes Medical Institute; Massachusetts General Hospital; Harvard Medical School
18:00	OPENING RECEPTION IN ROYAL PALM COURTYARD Sponsored by SynPep Corporation

SUNDAY, JUNE 19, 2005

08:00 - 08:07	WELCOME BY THE AMERICAN PEPTIDE SOCIETY PRESIDENT Jane V. Aldrich
08:07 - 08:15	WELCOME BY THE 19TH AMERICAN PEPTIDE SYMPOSIUM CO-CHAIRS Jeff Kelly & Tom Muir
SESSION I: GRAND BALLROOM	PEPTIDE AND PROTEIN SYNTHESIS STRATEGIES Chair: Richard A. Houghten
08:15 - 08:45  L1	NEW APPROACHES FOR SEQUENCE SCANNING TO IDENTIFY SECONDARY STRUCTURE IMPORTANT FOR PEPTIDE BIOLOGY Damien Boeglin - Rosa Melendez - Fabrice Galaud - Ramesh Kaul - Simon Surprenant - Mandar Bodas - William Lubell University of Montreal
08:45 - 09:05  O1	SYNTHESIS OF CYCLIC PEPTIDES VIA TRANSITION METAL CATALYZED C-C BOND FORMATION. Dirk TS Rijkers - Hefziba T ten Brink - Nourdin Ghalit - Jan Tois - Rob MJ Liskamp Department of Medicinal Chemistry; Utrecht Institute for Pharmaceutical Sciences; Utrecht University; POBox 80082; 3508 TB Utrecht; The Netherlands
09:05 - 09:25  O2	SOLID PHASE SYNTHESIS OF PHOSPHORYLATED CIS AND TRANS 3-PEPTIDYL-4-(4''-HYDROXYPHENYL) BETA-LACTAMS David Coleman - Kumar Kaluarachchi - John S. McMurray The University of Texas M. D. Anderson Cancer Center; The University of Texas Graduate School of Biomedical Sciences; The University of Texas M. D. Anderson Cancer Center Department of Neuro-Oncology; 1515 Holcombe Blvd.; Houston; TX 77030; The University of Texas M. D. Anderson Cancer Center; Department of Experimental Therapeutics; 1515 Holcombe Blvd.; Houston; TX 77030
09:25 - 09:55  L2	PEPTIDE-BASED CATALYSTS FOR ASYMMETRIC REACTIONS Scott Miller Boston College
ATLAS BALLROOM 10:00 - 10:30	REFRESHMENT BREAK IN EXHIBITION HALL
10:30 - 11:00  L3	CONSTRUCTION OF COMPLEX PROTEINS AND GLYCOPROTEINS USING CHEMICAL LIGATION Philip Dawson The Scripps Research Institute
11:00 - 11:20  O3	SWITCH ON AMYLOID b PEPTIDE SELF-ASSEMBLY BY ENZYME-TRIGGERED ACYL MIGRATION Manfred Mutter - S. Dos Santos - A. Chandravarkar - B. Mandal - R. Mimna - K. Murat - L. Saucede - M. Camus - G. Tuchscherer Ecole Polytechnique Fédéral de Lausanne (EPFL); Institute of Chemical Sciences and Engineering
11:20 - 11:40  O4	CUSTOMIZABLE SOLID-PHASE PEPTIDE SYNTHESIS Fernando Albericio Barcelona Science Park; University of Barcelona
11:40 - 12:00  O5	FERTILINbeta OLIGOPEPTIDES: DEPENDENCE OF FERTILIZATION INHIBITION ON LENGTH AND DENSITY Keith Baessler - Youn-Joo Lee - Kenny Roberts - Nicole Facompre - Nicole Sampson Stony Brook University; Leheigh University
12:00 - 12:20  O6	A NOVEL CHEMICAL LIGATION STRATEGY FOR THE CHEMICAL SYNTHESIS OF PROTEINS WITH NATIVE STRUCTURE Paolo Botti Geneprot Inc.; Geneva; Switzerland; University of Geneva; Switzerland
ATLAS BALLROOM 12:30 - 14:00	POSTER SESSION I & LUNCH IN EXHIBITION HALL Presenting Posters P001 - P150 odd numbers only
SESSION II: GRAND BALLROOM	BIOSYNTHESIS OF BIOACTIVE PEPTIDES Chair: Wilfred van der Donk
14:00 - 14:30  L4	REASSIGNING SENSE CODONS FOR RIBOSOMAL SYNTHESIS OF NOVEL TEMPLATE ENCODED POLYMERS Stephen Blacklow - Anthony Forster - Zhongping Tan - Virginia Cornish Brigham and Women's Hospital; Harvard Medical School; Vanderbilt University; Columbia University
14:30 - 15:00  L5	PEPTIDE MODULATORS OF G PROTEIN SIGNALING Richard Roberts - W. W. Ja - A. P. West - P. J. Bjorkman - S. Benzer Caltech Chemistry and Chemical Engineering; Caltech Chemistry and Chemical Engineering and Division of Biology California Institute of Technology
15:00 - 15:20  O7	RINGING THE CHANGES WITH VANCOMYCIN: A P450 CATALYZED OXIDATIVE PHENOL COUPLING REACTION John Robinson - Katharina Woithe - Dong Bo Li - Francesca Vitali - Laurent Bigler - Katja Zerbe University of Zurich
15:20 - 15:50  L6	CHEMOENZYMATIC APPROACHES TO NEW PEPTIDE ANTIBIOTICS Mohamed Marahiel Philipps University Marburg; FB Chemie
15:50 - 16:20  L7	SYNTHESIS AND BIOLOGICAL ASSESSMENT OF INSULIN-LIKE ANALOGS WITH DIFFERENTIAL ACTIVITY AT THE INSULIN AND IGF-1 RECEPTORS Jie Han - Amy Hoffman - Richard DiMarchi Indiana University
OPENING KEYNOTE: GRAND BALLROOM 16:20 - 17:20 L8	AN EXPANDED GENETIC CODE Peter G. Schultz The Scripps Research Institute; Genomics Institute of the Novartis Research Foundation
ATLAS BALLROOM 17:20 - 19:00	POSTER SESSION II & SOCIAL HOUR IN EXHIBITION HALL Presenting Posters P001 - P150 even numbers only Presenting Posters PYI - all Poster Competition participants

MONDAY, JUNE 20, 2005

SESSION III: GRAND BALLROOM	NEW THEMES IN ANTIMICROBIALS AND QUORUM SENSING Chair: Tom W. Muir
08:00 - 08:30  L9	THREADED RINGS AND COMPLEX TOPOLOGIES IN NOVEL ANTIMICROBIAL PEPTIDES: NATURE’S BIO-ENGINEERING TEMPLATES David Craik University of Queensland
08:30 - 09:00  L10	A MINIMALIST APPROACH TO ANTIMICROBIAL AGENTS WITH THIONIN AS A TEMPLATE David Andreu - Miquel Vila-Perelló - Sabrina Tognon - Andrea Sanchez-Vallet - Antonio Molina Pompeu Fabra University; Barcelona; Spain; UPM-ETSIA; Madrid; Spain
09:00 - 09:20  L10	DISCOVERY OF ADDITIONAL CHEMICAL AND BIOLOGICAL FUNCTIONS FOR 3-OXO-N-ACYLHOMOSERINE LACTONES Gunnar Kaufmann - Rafaella Sartorio - Sang-Hyeup Lee - Claude Rogers - Michael Meijler - Jason Moss - Bruce Clapham - Andrew Brogan - Tobin Dickerson - Kim Janda The Scripps Research Institute
09:20 - 09:50  L11	ANTIVIRAL CYCLIC DL-a-PEPTIDES: TARGETING A GENERAL BIOCHEMICAL PATHWAY IN VIRUS INFECTIONS W. Seth Horne - Christopher M. Wiethoff - Chunli Cui Cui -Keith M. Wilcoxen - Manuel Amorin - Glen R. Nemerow - Reza Ghadiri The Scripps Research Institute
09:50 - 10:10  O10	COMPARING ANTIMICROBIAL AND MEMBRANE PERMEABILIZING ACTIVITY OF PEPTIDES DERIVED FROM HUMAN CATIONIC PROTEINS Sylvie Blondelle - Susana Sánchez-Gómez - Jose Leiva-Leon - Ignacio Moriyon - Karl Lohner - Guillermo Martinez de Tejada Torrey Pines Institute for Molecular Studies; Medical School of the University of Navarra; Institute for Biophysics and X-ray Structure Research; Austrian Academy of Sciences
ATLAS BALLROOM 10:10 - 10:30	REFRESHMENT BREAK IN EXHIBITION HALL
10:30 - 11:00  L12	QUORUM SENSING AND INTERFERENCE BY BACTERIAL AUTOINDUCING PEPTIDES Richard Novick - J. Wright NYU School of Medicine
11:00 - 11:30  L13	POST-TRANSLATIONAL MODIFICATIONS DURING LANTIBIOTIC BIOSYNTHESIS Wilfred van der Donk University of Illinois; Department of Chemistry
MERRIFIELD AWARD AND LECTURE 11:30 - 12:30  L14	FROM TENS TO TRILLIONS: ADVANCES IN SYNTHETIC COMBINATORIAL AND DIVERSITY ORIENTED METHODS OVER THE PAST 20 YEARS Richard A. Houghten Torrey Pines Institute for Molecular Studies
ATLAS BALLROOM 12:30 - 14:00	POSTER SESSION III & LUNCH IN EXHIBITION HALL Presenting Posters P151 - P300 odd numbers only
SESSION IV: GRAND BALLROOM	POST-TRANSLATIONAL MODIFICATIONS OF PEPTIDES AND PROTEIN Chair: Philip Dawson
14:00 - 14:30  L15	CHEMICAL APPROACHES TO SORTING OUT PROTEIN PHOSPHORYLATION Philip Cole Johns Hopkins University
14:30 - 14:50  O11	ENZYMATIC INCORPORATION OF PRENYL AZIDES INTO PEPTIDES AND PROTEINS: TOOLS FOR SELECTIVE PROTEIN LABELING Mark Distefano University of Minnesota
14:50 - 15:20  L16	PROTEIN SEMI-SYNTHESIS AND ITS APPLICATION TO STUDIES OF STRUCTURE AND FUNCTION OF GTPASES Kirill Alexandrov - A Rak - O Pylypenko - T Durek - A Watzke - H Waldmann - RS Goody Max-Planck-Institute for Molecular Physiology; Otto-Hahn-Strasse 11; 44227 Dortmund; Germany
15:20 - 15:40  O12	N-ALKYLAMINOOXY AMINO ACIDS AS VERSATILE DERIVATIVES FOR 'POST-TRANSLATIONAL' MODIFICATIONS OF SYNTHETIC PEPTIDES Michael Carrasco Santa Clara University
15:40 - 16:00  O13	INFLUENCE OF POSTTRANSLATIONAL MODIFICATIONS ON BETA-HAIRPIN STABILITY Marcey Waters Department of Chemistry; UNC Chapel Hill
16:00 - 16:30  L17	CHEMICAL APPROACHES TO STUDYING PROTEIN GLYCOSYLATION IN THE BRAIN Linda Hsieh-Wilson California Institute of Technology
ATLAS BALLROOM 16:30 - 18:00	POSTER SESSION IV & SOCIAL HOUR IN EXHIBITION HALL Presenting Posters P151 - P300 even numbers only Presenting Posters PYI - all Poster Competition semi-finalists
18:30	SPEAKERS' DINNER AT SCRIPPS BIRCH AQUARIUM (by invitation only)

TUESDAY, JUNE 21, 2005

SESSION V: GRAND BALLROOM	GOODMAN MEMORIAL SESSION Sponsored by BACHEM, Inc. Chairs: Joseph P. Taulane and Richard A. Houghten
07:55 - 08:05  L18	MURRAY GOODMAN: PROFESSOR Joseph P. Taulane University of California; San Diego
08:05 - 08:30  L19	PROFESSOR MURRAY GOODMAN: A PIONEER OF PEPTIDE SCIENCE Fred Naider College of Staten Island; CUNY; Macromolecular Assemblies Institute
08:30 - 08:55  L20	PEPTIDES IN THE DAYS OF PHOTONICS Luis Moroder Max-Planck-Institute of Biochemistry
08:55 - 09:20  L21	IT ALL STARTED IN BROOKLYN FORTY-FIVE YEARS AGO! Claudio Toniolo Department of Chemistry; University of Padova; 35131 Padova; Italy
09:20 - 09:45  L22	PEPTIDE APPROACHES TO FOLDING AND ASSEMBLY OF TRANSMEMBRANE HELICES IN PROTEINS Charles M. Deber Structural Biology & Biochemistry; Research Institute; Hospital for Sick Children; Toronto
09:45 - 10:05  L23	OPIOID PEPTIDE ANALOG DESIGN: FROM CYCLIC ENKEPHALINS TO ORALLY ACTIVE ANALGESICS Peter W. Schiller Clinical Research Institute of Montreal; University of Montreal
10:05 - 10:15  L24	MURRAY GOODMAN: FORMIDABLE SENIOR FIGURE, FRIENDLY COLLEGIATE PEER, FATHERLY AND GENEROUS MENTOR Richard A. Houghten Torrey Pines Institute for Molecular Studies
ATLAS BALLROOM 10:15 - 10:45	REFRESHMENT BREAK IN EXHIBITION HALL
SESSION VI: GRAND BALLROOM	TOWARDS PEPTIDES AS POTENTIAL THERAPEUTICS I Sponsored by Senn Chemicals USA Chair: William D. Lubell
10:45 - 11:05  O14	CYCLIC MODULAR ß-SHEETS. James Nowick - Justin O. Brower - Omid Khakshoor - Wade A. Russu - R. Jeremy Woods University of California; Irvine
11:05 - 11:25  O15	IMPROVING ON NATURE: CONTROLLING THE SHAPE AND FUNCTIONALITY OF CYSTEINE RICH CONOTOXINS Paul Alewood Institute for Molecular Bioscience; The University of Queensland
11:25 - 11:55  L25	TARGET-BASED PROTEOLYTIC PROFILING FOR CHARACTERIZING CANCER PROGRESSION Gregg Fields Florida Atlantic University
11:55 - 12:15  O16	APOLIPOPROTEIN A-1 MIMETIC PEPTIDES G.M. Anantharamaiah - Mohamad Navab - Srinivas Reddy - Susan Hama - Greg Hogh - Mayaknoda Palgunachari - Geeta Datta - David Garber - Alan Fogelman University of Alabama at Birmingham; David Geffin School of Medicine at Los Angeles; University of Alabama at Birmingham Medical Center
12:15 - 12:45  L26	FROM SIMPLE CONSENSUS PEPTIDES TO HIGH AFFINITY LIGANDS: A STEPWISE DIVERSITY-ORIENTED STRATEGY FOR THE ACQUISITION OF POTENT SIGNALING INHIBITORS David Lawrence Albert Einstein College of Medicine
ATLAS BALLROOM 12:45 - 14:00	POSTER SESSION V & LUNCH IN EXHIBITION HALL Presenting Posters P301 - P600 odd numbers only
SESSION VII: GRAND BALLROOM	PEPTIDE AND PROTEIN DESIGN Chair: Jeff W. Kelly
14:00 - 14:30  L27	CONFORMATIONAL DIVERSITY AND CATALYSIS Donald Hilvert Swiss Federal Institute of Technology; ETH Hönggerberg
14:30 - 15:00  L28	FUNCTIONALIZED POLYPEPTIDES FOR PROTEIN RECOGNITION Lars Baltzer Department of Chemistry; Uppsala University
15:00 - 15:20  O17	BETA HAIRPIN MINIMIZATION AND OPTIMIZATION Niels Andersen - R. Matthew Fesinmeyer - K. A. Olsen University of Washington; same
15:20 - 15:50  L29	DESIGNED PEPTIDE MICROARRAYS FOR PROTEIN DETECTION AND CHARACTERIZATION Hisakazu Mihara - Kenji Usui - Kin-ya Tomizaki - Kiyoshi Nokihara Tokyo Institute of Technology; HiPep Laboratories
15:50 - 16:10  O18	ANALOGUES OF INTERLEUKIN 8 CONTAINING A beta-PEPTIDE SEGMENT SHOW HIGH BIOLOGICAL ACTIVITY Ralf David - Annette G. Beck-Sickinger University of Leipzig; Institut of Biochemistry; University of Leipzig
16:10 - 16:40  L30	PROBING MINIPROTEIN STABILITY VIA BACKBONE THIOESTER EXCHANGE Samuel H. Gellman University of Wisconsin
ATLAS BALLROOM 16:40 - 18:00	POSTER SESSION VI & SOCIAL HOUR IN EXHIBITION HALL Presenting Posters P301 - P600 even numbers only Presenting Posters PYI - all Poster Competition finalists
18:30	MERRIFIELD AWARD DINNER AT TRELLISES GARDEN GRILLE (by invitation only)

WEDNESDAY, JUNE 22, 2005

SESSION VIII: GRAND BALLROOM	PEPTIDE QUATERNARY STRUCTURES IN MATERIAL SCIENCE AND DISEASE Chair: Samuel H. Gellman
08:00 - 08:30  L31	DESIGNING NANO-TO-MICRON SCALE PEPTIDE-BASED SELF-ASSEMBLING SYSTEMS FROM THE BOTTOM UP Dek Woolfson - Maya Pandya - Max Ryadnov - Andrew Smith University of Sussex
08:30 - 09:00  L32	MECHANISMS OF AMYLOIDOGENESIS Evan Powers The Scripps Research Institute
09:00 - 09:20  O19	Peptide Reptation as a Mechanism for Rearrangements with a Beta-sheet Aggregate Sarah Petty - Sean Decatur Mount Holyoke College
09:20 - 09:50  L33	Cytocompatibility and antimicrobial activity of self-assembled beta hairpin hydrogels Joel Schneider - Juliana Kretsinger - Lisa Haines University of Delaware
ATLAS BALLROOM 09:50 - 10:30	REFRESHMENT BREAK IN EXHIBITION HALL
MAKINENI AWARD AND LECTURE 10:30 - 11:15  L34	MEDICINAL CHEMISTRY APPLIED TO A SYNTHETIC PROTEIN: THE PREVENTION OF INFECTION BY HIV Robin Offord Department of Structural Biology and Bioinformatics; University of Geneva
	LUNCH ON OWN - FREE AFTERNOON POSTER AND EXHIBITION HALL DISMANTLING Please check the bulletin board for reunion announcements

THURSDAY, JUNE 23, 2005

SESSION IX: GRAND BALLROOM	PEPTIDE AND PROTEIN ARRAYS Chair: Hisakazu Mihara
08:00 - 08:30  L35	A WIRING DIAGRAM FOR TYROSINE KINASE-MEDIATED SIGNALING USING PROTEIN MICROARRAYS Gavin MacBeath Harvard University
08:30 - 08:50  O20	HIGH DENSITY PEPTIDE CHIP FOR QUANTITATIVE MEASUREMENTS OF PROTEIN BINDING AND ENZYMATIC ACTIVITIES Xiaolian Gao Department of Biology&Biochemistry; The University of Houston
08:50 - 09:10  O21	DNA-PROTEIN ARRAYS AS TOOLS FOR DETECTION OF PROTEIN-PROTEIN INTERACTIONS BY MASS SPECTROMETRY Christian F.W. Becker - Ron Wacker - Werner Bouschen - Ralf Seidel - Branko Kolaric - Hendrick Schroeder - Christof Niemeyer - Bernhard Spengler - Roger Goody - Martin Engelhard Max-Planck Institute of Molecular Physiology; Chimera Biotec GmbH; Emil-Figge-Str. 76A; 44227 Dortmund; Germany; Justus-Liebig Universität Giessen; Schubertstr. 60; 35392 Giessen; Germany; Max-Planck-Insitut für molekulare Physiologie; Otto-Hahn-Str. 11; 44227 Dortmund; Germany; Max-Planck-Institut für molekulare Physiologie; Otto-Hahn-Str. 11; 44227 Dortmund; Germany; Universität Dortmund; Otto-Hahn-Str. 6; 44227 Dortmund; Germany
09:10 - 09:40  L36	MONITORING AND MANIPULATING THE PROTEOME WITH PEPTIDES AND PEPTOIDS Thomas Kodadek UT-Southwestern Medical Center
09:40 - 10:00  O22	NEW TOOLS FOR THE SITE-SPECIFIC ATTACHMENT OF PROTEINS TO SURFACES Julio A. Camarero - Youngeun Kwon - Matthew A. Coleman Lawrence Livermore National Laboratory; University of California
GRAND FOYER 10:15 - 10:45	REFRESHMENT BREAK
SESSION X: GRAND BALLROOM	TOWARDS PEPTIDES AS POTENTIAL THERAPEUTICS II Chair: Fernando Albericio
10:30 - 10:50  O23	UNDERSTANDING BBB TRANSPORT USING GLYCOSYLATED ENKEPHALINS & ENDORPHINS Robin Polt - M. Dhanasekaran - I. Alves - C.M. Keyari - L. Yeomans - R.E. Egleton - J.M. Bidlack - H.I. Yamamura - V. J. Hruby - E.J. Bilsky The University of Arizona; Carl S. Marvel Laboratories of Chemistry; Dept. of Pharmacology; Univ. of Arizona; Tucson; AZ 85721; U.S.A.; Univ. of Rochester Medical Center; Rochester; NY 14642; U.S.A.; Dept. of Pharmacology; University of New England; Biddeford; ME 04005
10:50 - 11:10  O24	T CELL SPECIFICITY EXAMINED IN A SYSTEMATIC AND COMPREHENSIVE MANNER USING PEPTIDE POSITIONAL SCANNING LIBRARIES Clemencia Pinilla - Mireia Sospedra - Yindong Zhao - Richard Simon - Roland Martin Torrey Pines Institute for Molecular Studies; NINDS; NIH; NCI
11:10 - 11:30  O25	SCREENING BIOSYNTHETIC PEPTIDE LIBRARIES FOR ANTIMICROBIAL ACTIVITY Lisa Nilsson - Mostafa Louassini - Ernesto Abel-Santos Albert Einstein College of Medicine
11:30 - 11:50  O26	DESIGN AND STUDY OF NOVEL PEPTIDE INHIBITORS AGAINST SARS-COV ENTRY Brian Tripet - Robert Hodges - Zhe Yan University of Colorado Health Sciences Center at Fitzsimons
11:50 - 12:10  O27	A BI-DIRECTIONAL PEPTIDE SWITCH: ƒÑ-HELICAL COILED COIL INTERACTION VERSUS ƒÒ-SHEET FORMATION Beate Koksch Free University Berlin; Department of Chemistry - Organic Chemistry; Takustr. 3; 14195 Berlin
12:10 - 13:10	LUNCH ON OWN
SESSION XI: GRAND BALLROOM	PROTEOMICS AND EMERGING TECHNOLOGIES Chair: Tom Kodadek
13:10 - 13:30  O28	RDC AS A NEW NMR-PARAMETER FOR PEPTIDES Horst Kessler - Burkhard Luy - Kyryl Kobzar - Christoph Freudenberger - Sebastian Knor - Dominik Heckmann Department Chemie; TU Munich; Lichtenbergstr.4; 85747 Garching; Department Chemie; TU Munich; Lichtenbergstr.4; 85747 Garching; Germany
13:30 - 14:00  L37	NEW APPROACHES IN PROTEIN SPLICING TO CONTROL PROTEIN STRUCTURE AND FUNCTION Henning Mootz Philipps-Universität Marburg; Fachbereich Chemie; Hans-Meerwein-Str.; D-35032 Marburg
14:00 - 14:20  O29	EXAMINATION OF THE ROLE OF LIPID RAFTS IN GPCR SIGNAL TRANSDUCTION USING PLASMON WAVEGUIDE RESONANCE (PWR) SPECTROSCOPY Victor J. Hruby - Isabel D. Alves - Zdzislaw Salamon University of Arizona; American Chemical Society; American Peptide Society; Department of Chemistry University of Arizona; Department of Biochemistry & Molecular Biophysics University of Arizona
14:20 - 14:40  O30	IMAGING PROTEASE ACTIVITY USING NOVEL FLUORESCENTLY QUENCHED PROBES Galia Blum - Georges von Degenfeld - Kinneret Keren - Helen Blau - Matthew Bogyo Stanford University
14:40 - 15:10  L38	CHEMICAL GENETIC ANALYSIS OF CELLULAR SIGNAL TRANSDUCTION Kevan Shokat Department of Cellulalar and Molecular Pharmacology; UC San Francisco; Department of Chemistry; UC Berkeley
CLOSING KEYNOTE: GRAND BALLROOM 15:10 - 16:10  L39	ENZYMATIC HALOGENATION OF AMINO ACID MOIETIES IN NATURAL PRODUCTS: OXIDATIVE STRATEGIES Christopher Walsh Harvard University
18:15	CLOSING BANQUET FESTIVITIES BEGIN IN THE ROYAL PALM COURTYARD
19:15	CLOSING BANQUET IN THE GRAND BALLROOM
20:15	SAN DIEGO'S VINTAGE AND CLASSIC ROCK BAND: ROCKOLA